Local Anesthetics (2)
Local anesthetics were analyzed using RSpak
DE-413 (a
column for reversed phase chromataography) with alkaline eluent.
Please refer to
Analysis of Short Amines without Using Ion Pair Reagent.
Sample : 10micro-L
1.
Benzocaine 20micro-g/mL
2.
Lidocaine 100micro-g/mL
3.
Tetracaine100micro-g/mL
Column : Shodex RSpak DE-413 (4.6mmID*150mm)
Eluent : 20mM Sodium phosphate buffer(pH9.0)/CH3CN=50/50
Flow rate : 0.8mL/min
Detector : UV(254nm)
Column temp. : 40deg-C