Nucleosides (5) (AIA-894)
The ligand of AFpak
AIA-894 (an affinity column) is iminodiacetic
acid. A custom column which is co-ordinated with cupper ion was used for the analysis
of ribonucleosides. First, ribonuclosides were adsorbed, and then, released by
0.05M ethylmorpholine acetate(pH6.0). The sample was separated into four peaks.
Sample :
1.
Uridine
2.
Cytidine
3.
Guanosine
4.
Adenosine
5.
2'-Deoxyadenosine
Column : Shodex AFpak AIA-894 (8.0mmID*50mm) (Cu co-ordinated using 0.05M cupric sulfate aq.)
Eluent : 0.05M Ethylmorpholine acetate buffer(pH6.0)
Flow rate : 1.0mL/min
Detector : UV(280nm)
Column temp. : Room temp.